Reproducible Model
Original Article
Published: 2020-08-26
Last edited: 2020-08-26
Bond Graph Model of Cerebral Circulation: Toward Clinically Feasible Systemic Blood Flow Simulations
Su, S.
,
Blanco, P. J.
,
Müller, L. O.
,
Hunter, P. J.
,
Safaei, S.
 View publication
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To cite this Physiome article, cite the whole collection at the DOI: 10.36903/physiome.12859424, and the Primary Publication at the DOI: https://doi.org/10.3389/fphys.2018.00148. All Physiome articles are published as a collection containing the manuscript as a PDF file and the model implementation as an OMEX file. |
Primary Publication: Bond Graph Model of Cerebral Circulation: Toward Clinically Feasible Systemic Blood Flow Simulations. 2018, Safaei, S., Blanco, P. J., Müller, L. O., Hellevik, L. R. and Hunter, P. J.
Abstract: The primary paper Safaei et al. (2018) proposed an anatomically detailed model of the human cerebral circulation that runs faster than real-time on a desktop computer and is designed for use in clinical settings when the speed of response is important. Based on a one-dimensional formulation of the flow of an incompressible fluid in distensible vessels, a lumped parameter model was developed for 218 arterial segments. The proposed model improved simulation speed by approximately 200-fold while preserved accuracy. Bond graph formulation was used to ensure mass and energy conservation. The model predicted the pressure and flow signatures in the body.
References:
1. Bond Graph Model of Cerebral Circulation: Toward Clinically Feasible Systemic Blood Flow Simulations. Journal: Frontiers in Physiology. Safaei, Soroush and Blanco, Pablo J and Müller, Lucas O and Hellevik, Leif R and Hunter, Peter J. Volume: 9. Year: 2018.
2. An anatomically detailed arterial network model for one-dimensional computational hemodynamics.. Journal: IEEE Transactions on Biomedical Engineering. Blanco, Pablo J and Watanabe, Sansuke M and Passos, Marco Aur{\'e}lio RF and Lemos, Pedro A and Feij{\'o}o, Ra{\'u}l A. Volume: 62. Year: 2015.
3. Blood flow distribution in an anatomically detailed arterial network model: criteria and algorithms. Journal: Biomechanics and Modeling in Mechanobiology. Blanco, Pablo J and Watanabe, Sansuke M and Dari, Enzo A and Passos, Marco Aur{\'e}lio RF and Feij{\'o}o, Ra{\'u}l A. Volume: 13. Year: 2014.
4. A dimensionally-heterogeneous closed-loop model for the cardiovascular system and its applications. Journal: Medical Engineering \& Physics. Blanco, Pablo J and Feij{\'o}o, Ra{\'u}l A. Volume: 35. Year: 2013.